Mast Cells and Prostatitis CP/CPPS

Mast cells, stress and prostatitis: brief overview

Mast cells are players in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and bladder pain syndrome/interstitial cystitis (BPS/IC). They degranulate and promote inflammation both under stress-invoked neurological and food-related allergic stimuli. IC researcher TC Theoharides has shown that mast cells are not only involved in allergic reactions, but also that they are necessary to initiate inflammation, thus participating in inflammatory diseases that worsen by stress, such as CP/CPPS, autism, cancer, chronic fatigue syndrome, interstitial cystitis, migraine headaches, psoriasis and multiple sclerosis.

mast cells prostatitis

Stress Increases Number of Mast Cells in Bladder

In murine (rat) studies, researchers found that stress exposure led to pathological bladder changes, including an increased number of mast cells, degenerated urothelium and dilated tight junctions, in the bladder. They also found that that mast cells are involved in neurogenic cystitis induced by changes in CNS activity.

This suggests that the brain can cause inflammation in organs like the bladder by stimulating mast cells via the nervous system. Mast cells interact with innervating nerve fibres. If your pelvic muscles are tense because your brain is subconsciously telling them to tense up, then the ends of the nerves that are maintaining the high pelvic muscle tonus are “buzzing” with electrical impulses, to put it simply, and they communicate with nearby mast cells in the bladder, prostate, urethra, testicles etc.

This is a very complex area of medicine beyond the scope of this website, but the bottom line for patients is the concept that stress can activate mast cells in different parts of the body. Once activated, they degranulate, releasing numerous chemicals that promote inflammation, like histamine and several cytokines. Two ways to combat this are 1) Prosta-Q or Q-Urol, which protect mast cells and inhibit degranulation, and 2) unwinding the brain-sourced stress and muscular tension.

mast cells

Throw out the antibiotics and try these….


Q-Urol for prostatitis

Buy 1 get 1 FREE! Remember, use code 50UROL18. There is no better anti-prostatitis medication on the market, period. Q-UROL offers all of the benefits of Prosta-Q, but with time release technology and extra strength anti-inflammatory power. Published studies prove that both quercetin and pollen extract (also known as cernilton) calm CPPS symptoms. The combination is very effective for the majority of patients, and has been shown in published urological studies to help maintain prostate health and specifically target pelvic or genital discomfort.


BP-Qmax for prostatitis and BPH

Buy 1 get 1 FREE! Remember, use code 50QMAX19. BPH and Prostatitis share many symptoms. The proprietary blend of clinically proven all-natural ingredients found in BP-Qmax was developed in collaboration with leading urologists at major medical centers to assist men with prostate and urinary health issues and provide support for those seeking powerful, but natural, prostate health support. Contains optimum amounts of Beta-Sitosterol, Saw Palmetto, Flower Pollen and enzymes, as studied by academic urologists. Reduce nighttime urination and sleep through the night with BP-QMax™

TriverexMD and Trinoboost

trinoboost and triverex for libido repair

Buy 1 get 1 FREE! Remember, use code 30TRIN456. Trinoboost increases levels of nitric oxide (NO), vital for erections. TriverexMD contains Panax Ginseng, which has extensive clinical evidence (7 human clinical studies) proving effective for boosting male sexual health, especially erectile dysfunction. Try these natural remedies and avoid harmful ED drugs.


Multiright acide free vitamins

Buy 1 get 1 FREE! Remember, use code 2Multi3295. MultiRight is the only pH neutral, low acid multivitamin which means that it’s more bladder friendly than ever!  Most multivitamins are acidic (usually because of the cheap form of Vitamin C they contain) and can burn inflamed bladders, prostates and urethras. This product won’t do that. Kill the burn now!

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