At Last, Something that Helps Many
Quercetin is a plant-derived bioflavonoid with a wide range of effects. It is an anti-cancer agent, it affects the immune system, protects mast cells and even has an antimicrobial effect. It is also useful in treating musculoskeletal conditions.
Dr Shoskes, who discovered that quercetin could help many chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients, theorises that quercetin decreases inflammation and oxidant stress in the prostate while increasing local concentrations of beta-endorphins. He says that quercetin has also been shown to inhibit the induction and function of T cells in vitro, so it may be able to short-circuit the root cause of autoimmunity (presuming autoimmunity is involved in CP/CPPS). Its general properties are: anti-oxidant, tyrosine kinase inhibitor, nitric oxide inhibitor, anti-inflammatory (inhibits NF-kB, blocks PGE-2 and cox-2 gene expression) and inhibitor of histamine and cytokine release from mast cells (quercetin inhibits the release of histamine, leukotrienes (LTs), prostaglandin D2 (PGD2), and granulocyte macrophage-colony stimulating factor (GM-CSF) from human cultured mast cells).
ProstaQ: The only form of quercetin studied for use against prostatitis, ProstaQ capsules are recommended by academic urologists. A recent study suggests that this patented proprietary formulation is more effective than generic quercetin. Specially processed from US raw materials in Switzerland to guarantee total purity, its secret formula (containing a patented blend of bromelain, papain, cranberry powder, black cohosh root, skullcap, wood betany leaf, passionflower and valerian root) ensures a higher absorption rate. Read a leading urologist's views about ProstaQ & CP/CPPS. Yet another study on ProstaQ.
There have been numerous messages to the Usenet newsgroup on prostatitis
by men heaping praise on this flavonoid, while a small proportion
insist they have not been helped. Many of those not helped are taking
cheap and unreliable brands of quercetin and aren't getting the
right dose (the most reliable brand is Prosta-Q). Dr Shoskes says
that "Some patients notice improvement after the first few
doses. For others it can take up to a month to work." But like
most medicines used to treat disease, quercetin does not help all
sufferers, probably because of genetic differences between people.
However everyone with CP/CPPS should try it, because they may be
one of the fortunate who are helped.
Some people like the idea that quercetin is having antibacterial effects (which studies have documented). But Dr Shoskes says "Quercetin MAY have effects on antibiotic resistant bacteria. I should emphasize that I have not found quercetin to be helpful clinically in my patients with documented infections."