Central Sensitization and Pelvic Pain

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webslave
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Central Sensitization and Pelvic Pain

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A A Case Rep. 2016 Jun 1;6(11):364-5. doi: 10.1213/XAA.0000000000000318.
The Great Deceiver: A Case of Central Sensitization Presenting as Carcinoid Syndrome.
Ramos JA.
From the Department of Anesthesiology, Division of Pain Medicine, University of Florida Health, Gainesville, Florida.


Central sensitization defines a state of amplified sensory input within the nervous system across many organ systems; it overlaps syndromes as fibromyalgia, chronic fatigue, irritable bowel, and interstitial cystitis. Commonly, individuals will experience multiple syndromes during the course of their lifetime. A 62-year-old patient presented for evaluation of multiple medically unexplained symptoms postsurgically including chronic left chest wall and flank pain with concomitant diarrhea, abdominal pain, and facial flushing. After extensive multidisciplinary evaluations, he was diagnosed as having central sensitization in which the initial presentation mimicked carcinoid syndrome. He was subsequently treated with extensive multidisciplinary pain rehabilitation, and did well.

PMID: 27144900
[PubMed] - in process
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Central Sensitization
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mshaqal
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Re: Central Sensitization and Pelvic Pain

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What you think about this:
Fluvoxamine (Luvox) May Be Helpful in Prostatodynia
http://www.medscape.com/viewarticle/441575
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Re: Central Sensitization and Pelvic Pain

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Yes, well, there is some evidence SSRIs can be helpful, probably because of anxiolytic effects, although there may be some direct action on pain via central mechanisms.

http://pubmed.ncbi.nlm.nih.gov/21933619
http://124.205.33.103:81/ch/reader/view ... 110&flag=1
http://pubmed.ncbi.nlm.nih.gov/18441724
http://pubmed.ncbi.nlm.nih.gov/15800093
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Re: Central Sensitization and Pelvic Pain

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ssri-potency.gif
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receptors where different SSRI work on.
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