NIDDK Meeting in Washington on Pelvic Pain

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October 30 - November 1 2003, Radisson Hotel, Alexandria, VA

CLINICAL REPORTS AND UPDATES

Interstitial Cystitis Clinical Trials Group (ICCTG)
UK Pelvic Pain Database
Chronic Pelvic Pain/Prostatitis Treatment Group
Research Priorities for Interstitial Cystitis
International Consultation on Interstitial Cystitis, Kyoto, Japan, 2003 Report


THURSDAY, OCTOBER 30

Registration

Welcome (A. Spiegel / V. Ratner)

Introductory Address: 1988 Interstitial Cystitis Research Criteria -- Perspectives 15 Years Later (A. J. Wein)

SESSION I

Interstitial Cystitis and Related Pain Syndromes: Where Are the Boundaries?
(U. Wesselmann, Chair)

Vulvodynia and IC (U. Wesselmann)

Overlap of Bladder and Bowel Dysfunction (E. M. Mayer)

Gynecologic Perspective of IC and Chronic Pelvic Pain (F. M. Howard)

Musculoskeletal Problems and CPP (R. D. Gerwin)

Pelvic Pain in Men -- IC and Prostatitis (R. B. Alexander)

Moderated Panel Discussion (C. Whitmore, Moderator)

BREAK

SESSION II

Inflammation and Signaling (D. Klumpp, Chair)

Role of Reactive Oxygen Species in Bladder Smooth Muscle Mechanotransduction
(J. M. Park)

The Urothelial Cell as an Active Participant in Bladder Mucosal Immune Responses
(M. O'Donnell)

Role of Protease-Activating Receptors (PARSs) 1,2,3, and 4 in Acute and Chronic Experimental Bladder Inflammation (R. Saban)

TNF-Alpha in Bladder Inflammation (D. Klumpp)

Moderated Panel Discussion (D. Bjorling)

LUNCH

KEYNOTE SPEAKER

Insights into Pathophysiology of Chronic Urinary Tract Infections (S. Hultgren)

Discussion (D. Klumpp, Moderator)

SESSION III

Bladder Neuroplasticity and Chronic Inflammation (M. Vizzard, Chair)

Pathology-Induced Changes in the Properties of Bladder Afferent Neurons
(N. Yoshimura)

Cystitis-Induced Plasticity of Micturition Reflexes (M. Vizzard)

BREAK

Pharmacotherapy for the Painful Bladder (W. C. de Groat)

Sacral Neuromodulation in Treatment of IC Symptoms (T. Chai)

Moderated Panel Discussion (T. Ness, Moderator)

NEUROIMAGING IN LOWER URINARY TRACT DYSFUNCTION (C. Fowler)


Questions and Discussion


FRIDAY, OCTOBER 31


SESSION IV

Insights into Urothelial Function (D. Erickson, Chair)

Antiproliferative Factor -- An Update (S. Keay)

Title TBA (M. L. Zeidel)

Title TBA (J. Bassuk)

Moderated Panel Discussion (D. Erickson, Moderator)

SESSION V

Detrusor Function and Regulation (P. Howard, Chair)

Botulinum Toxin (Botox) Applications to Urinary Bladder Muscle and IC (M. Chancellor)

P2X Receptors and ATP Regulation of Urinary Bladder Function (D. A. Cockayne)

Vanilloid Receptors in Urothelium (L. Birder)

Moderated Panel Discussion (P. Howard)

BREAK

SESSION VI

Clinical Management of Chronic Pain (T. Ness, Chair)

Genetic and Environmental Aspects of Pain (M. Devor)

Physical Therapy Perspectives on Pelvic Pain (R. Kotarinos)

Pharmacology of Pain Management; Implications for Pelvic Pain (D. J. Hewitt)

The Future of Multidisciplinary Pain Management (D. B. Carr)

Moderated Panel Discussion (T. Ness)

LUNCH

Lessons from the UK Pelvic Pain Database (S. Kennedy)

Prize Winning Poster Abstract Presentations (6 posters)

BREAK

Poster Session with Authors


SATURDAY, NOVEMBER 1

SESSION VII

The Future: Novel Treatments for IC and CPP (C. Payne, Chair)

Intravesical Botox (R. Rackley)

Sacral Nerve Stimulation (K. Peters)

Vanilloid Therapies -- RTX and Capsaicin (M. Chancellor)

IPD-1151T (T. Ueda)

Moderated Panel Discussion (J. Nordling, Moderator)

Gene Therapy for Bladder Dysfunction (N. Yoshimura)

Questions and Discussion

BREAK

International IC Meeting Summaries

Japan Summary (T. Ueda)

Denmark Summary (J. Nordling)

Report from ICCTG (H. Foster)

Report from CPPTG (C. Nickel)

SESSION VIII

The Interstitial Cystitis Diagnostic Criteria Revisited -- An Evidenced-Based Definition: Where We Are, What We Need. A Report from the Clinical Subcommittee (C. Payne, Chair)

Urodynamic Studies (W. Bushman)

Cystoscopy, Bladder Distention, Bladder Biopsies (M. Pontari)

Potassium Sensitivity Testing (C. Payne)

Antiproliferative Factor and Other Biomarkers (C. L. Parsons)

History, Physical Exam and Questionnaires (G. R. Sant)

Moderated Panel Discussion on Definition of Disease (P. Hanno, Moderator)

(Conference is scheduled to adjourn at 1 pm)