bid working as well as Clarinex qod, but without the liver cancer worries with long term use (Claritin/Clarinex cause cancer in mice at high doses). Only downside is a slight "clenching" of the prostate about twice a day, soon after taking dose, as happened with hydroxyzine, but not nearly
as bad as hydroxyzine, so no need for alpha blocker. None of the antihistamines is completely
free of this side effect. I must say, my stream is far slower and thinner now than when taking Hytrin. However, I also have no heartburn any more, and I wonder if I will ever be able to tolerate alpha blockers because unfortunately I get this lower esophogeal sphincter relaxation with acid reflux reaction
Now for the good news: started Zantac
yesterday, 75mg qod. Ate items known to cause me stomach pain on waking ... and awoke with no pain! This is an auspicious beginning! I'll reserve judgement to see if this lasts (as we all know, often things that help don't keep on helping).
I am trying Zantac with Allegra in my quest to create a "histamine blockade"
in my body, based on the theory that mast cells and histamine are behind most of our woes. I started Zantac, an antihistmine that acts on receptors in the gut rather than in the skin and brochii, and which is better known as an antacid
, because women with IC are reporting that cimetidine (Tagamet)
, very similar to Zantac, is helpful.
The remaining thing I must look to in the cascade that follows mast cell degranulation is what's called the "late phase reaction", impossible to control as far as I know, in which prostaglandins