J Urol. 2013 Jan 12. pii: S0022-5347(13)00046-3. doi: 10.1016/j.juro.2013.01.020. [Epub ahead of print]
A subtypes based analysis of Urological Chronic Pelvic Pain Syndrome in men.
Davis SN, Binik YM, Amsel R, Carrier S.
Department of Psychology, McGill University, Montreal, Canada.
PURPOSE: The current conceptualization of Urological Chronic Pelvic Pain Syndrome (UCPPS) in men recognizes a wide variety of pain, psychosocial, sexual, and urological symptoms and markers that may contribute to lowered quality of life. Unfortunately, this syndrome is difficult to clearly define and treat due to heterogeneous symptom profiles. The present study systematically described these heterogeneous symptoms and investigated whether these symptoms can be subtypes into distinct syndromes.
MATERIALS AND METHODS: 171 men diagnosed with UCPPS filled out validated questionnaires, a structured genital pain interview, digital pain threshold testing, and urological assessment. The results of the pain interview are systematically presented as descriptive information. In addition, k-means cluster analysis was employed to define subtypes.
RESULTS: Seven homogenous and distinct clusters were defined, each with remarkably different symptom presentation. These clusters were then described and related to previous hypotheses of UCPPS etiology.
CONCLUSIONS: These clusters may represent distinct subtypes of UCPPS, and can then be used to guide treatments more effectively. Definition of subtypes may also improve understanding of the underlying mechanisms in UCPPS.
UCPPS and Psychological Subtypes
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UCPPS and Psychological Subtypes
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