NIDDK to Fund Gene Expression Studies of CPPS

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NIDDK to Fund Gene Expression Studies of Chronic Pelvic Pain Disorders
November 28, 2012
By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – The National Institute of Diabetes and Digestive and Kidney Diseases plans to spend $1.5 million next year to fund a number of studies that will explore the molecular anatomy of pain receptors that are associated with pain in the urinary tract and pelvic region.

These studies will generate knowledge about the genes and gene and protein expression activities in patients who perceive chronic pain in the pelvis or urogenital floor, which is a primary feature of painful bladder syndrome (PBS) and chronic pelvic pain syndrome (CPPS).

The focus of these studies will be on understanding the molecular landscape of nociceptors and associated cell types that are involved in the chronic pain sensations that afflict these PBS and CPPS patients. The larger aim of such research is to use this knowledge to develop ways to reduce this nociceptor activity or to block their input into the central nervous system.

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