Search found 27 matches

by boulder
Wed Jan 19, 2011 11:52 am
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 24
Views: 5574

Re: Could Viagra cure chronic pelvic pain?

Hi NYanchuk, Thank you for asking, as I'd been meaning to update this thread. I eventually decided that Cialis (tadalafil) did not seem to be having any great effect on my pain/discomfort (see reasons 2 and 3 in my post above above for why). However, it most certainly has been effective for me in tr...
by boulder
Mon Jun 15, 2009 5:43 am
Forum: Research News & Updates
Topic: NIH BIOMARKER/GENETIC STUDY
Replies: 9
Views: 820

Re: NIH BIOMARKER/GENETIC STUDY

By the way, does anyone know if this is related to the NIH's Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP)? It appears to be separate, but I wonder... There would seem to be significant overlap in stated goals. Maybe there's a distinction I'm missing?
by boulder
Sun Jun 14, 2009 3:51 pm
Forum: Research News & Updates
Topic: NIH BIOMARKER/GENETIC STUDY
Replies: 9
Views: 820

Re: NIH BIOMARKER/GENETIC STUDY

I may have misunderstood what you were saying, Rufus, but I wanted to note that just because CPPS may have a hereditary/genetic component doesn't mean it isn't muscle related. A genetic predisposition could lead to neuromuscular pathology. And finding reliable biomarkers is important regardless. Res...
by boulder
Mon Jun 08, 2009 10:37 pm
Forum: Research News & Updates
Topic: NIH BIOMARKER/GENETIC STUDY
Replies: 9
Views: 820

Re: NIH BIOMARKER/GENETIC STUDY

Great find, Rufus! Nobody else has commented on this yet, but this seems like extremely good news, doesn't it?
by boulder
Sat May 09, 2009 6:51 pm
Forum: Research News & Updates
Topic: UPOINT website
Replies: 3
Views: 423

Re: UPOINT website

Dr. Shoskes, thank you so much for your work on the UPOINT system and now this very useful website! I'm sure they will be a great help to doctors and patients alike in navigating treatment of this complex condition. I do have one question: I wonder what role, if any, you see for muscle relaxants in ...
by boulder
Thu Apr 30, 2009 2:30 am
Forum: Research News & Updates
Topic: AUA 2009: Pregabalin (Lyrica)
Replies: 8
Views: 885

Re: AUA 2009: Pregabalin (Lyrica)

It's too bad that this trial didn't turn out better for pregabalin. It is wonderful, however, to see effort and resources dedicated to such large trials! I don't really understand what's meant by the difference between the primary and secondary endpoints in this study, am I right to think that prega...
by boulder
Wed Sep 17, 2008 6:06 pm
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 24
Views: 5574

Re: Could Viagra cure chronic pelvic pain?

As promised, here's an update on my experience with Cialis (tadalafil). Please keep in mind that this is just the experience of one guy. I'm not a doctor and this is not medical advice... I'm taking Cialis 10mg/day, as prescribed by my doctor, and have been for 3 months now. Prior to that I took Cia...
by boulder
Fri Jun 13, 2008 8:01 pm
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 24
Views: 5574

Re: Could Viagra cure chronic pelvic pain?

Just a dosage update for anyone who's curious: I am now taking Cialis 10mg/day, as prescribed by my doctor. As I said before, I'll wait a few months to report on my experience.
by boulder
Sat May 31, 2008 7:19 pm
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 24
Views: 5574

Re: Could Viagra cure chronic pelvic pain?

Taking another look at the above study (Cialis/alfuzosin combo therapy), my layman's eye noticed that the dosing of Cialis seems odd: 20mg 3 times a week? Even with Cialis' relatively long half-life, you'd think that would give you widely fluctuating levels of the drug in the body...
by boulder
Fri May 23, 2008 8:10 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1393

Re: ALFUZOSIN VS. PLACEBO

A 2006 study by Dr. Nickel found alfuzosin 10mg/day beneficial for LUTS, ED, and painful ejaculation : http://pubmed.ncbi.nlm.nih.gov/16686719 BJU Int. 2006 Jun;97(6):1242-6. The beneficial effect of alfuzosin 10 mg once daily in 'real-life' practice on lower urinary tract symptoms (LUTS), quality o...
by boulder
Fri May 23, 2008 7:32 am
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 24
Views: 5574

Re: Could Viagra cure chronic pelvic pain?

Hmm, and this one relates to both Cialis and Uroxatral (alfuzosin) in combination ... [1251] COMBINATION OF AN ALFUZOSIN XL AND TADALAFIL IS SUPERIOR TO MONOTHERAPY IN TREATING ERECTILE DYSFUCTION (ED) AND LOWER URINARY TRACT SYMPTOMS (LUTS) Gyung-woo Jung*, Jun Heo, Busan, Republic of Korea INTRODU...
by boulder
Fri May 23, 2008 2:44 am
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 24
Views: 5574

Re: Could Viagra cure chronic pelvic pain?

Wow. That's the same dosage (10mg) I was thinking of and everything! And, actually, I was wrong earlier when I said the FDA hadn't approved Cialis 10mg for daily use. Technically, the FDA allows up to 20mg/day: November 21, 2003 FDA Approves Third Drug To Treat Erectile Dysfunction http://www.fda.g...
by boulder
Thu May 22, 2008 1:00 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1393

Re: ALFUZOSIN VS. PLACEBO

Hmm, this is interesting to me, as I was one of the forum members who thought he'd found positive benefits from alpha blockers! In fact, I mentioned it in the very first thread I posted on: https://www.ucpps.men/forum/viewtopic.php?f=37&t=4297&p=22814#p22814 However, now that I think about i...
by boulder
Thu May 22, 2008 12:22 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1393

Re: ALFUZOSIN VS. PLACEBO

There was a response of 49% in placebo arm and 49% in the alfuzosin arm! This result does not support the use of alfuzosin in the treatment of CP. Well, that certainly sounds quite final about alfuzosin (Uroxatral). Or maybe I'm over-eager to cross things off my list? Alpha-blockers relax smooth mu...
by boulder
Mon May 19, 2008 3:25 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1393

Re: ALFUZOSIN VS. PLACEBO

OK, thanks anyway, Dr. Dimitrakov! Paging Dr. Shoskes... :-D