Search found 326 matches

by J Dimitrakov
Fri Jun 06, 2008 9:26 pm
Forum: Research News & Updates
Topic: Adrenocortical Hormone Abnormalities in Men with CP/CPPS
Replies: 158
Views: 6128

Re: Adrenocortical Hormone Abnormalities in Men with CP/CPPS

This thread has gone somewhat quiet, just wondered if studies were continuing or if research has slowed down for the time being pending funding/project approvals etc? Research is being conducted on a larger scale to independently confirm the findings. We will report on the results as soon as they b...
by J Dimitrakov
Fri Jun 06, 2008 9:24 pm
Forum: Research News & Updates
Topic: Levofloxacin shows some use for newly diagnosed folks
Replies: 2
Views: 293

Re: Levofloxacin shows some use for newly diagnosed folks

Thanks for posting this, popburner. While I agree with your general thoughts about trying to identify and eliminate potential triggers, I am having trouble understanding the conclusions of the study. First off, the number of patients per group (26, 26, 29) is quite small and based on a simple statis...
by J Dimitrakov
Tue May 27, 2008 12:58 am
Forum: Research News & Updates
Topic: New genetic studies
Replies: 2
Views: 293

Re: New genetic studies

Hi, Kevin, Thanks for the opportunity to clarify. The two new studies should be posted on the announcement page, i.e. "Linkage Analysis in Interstitial Cystitis" and "Diagnostic Challenges in IC (and Male CPPS)" . The first study is our genomics-based study which involves a saliva sample from which ...
by J Dimitrakov
Sun May 25, 2008 3:36 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1015

Re: ALFUZOSIN VS. PLACEBO

Dr. Dimitrakov, I just wanted to thank you for posting so much interesting information, and more currently, for keeping us updated on interesting reports at the AUA meeting. For what it's worth, my experience with Flomax has been similar to latte's. I've been on it for about four months now, since ...
by J Dimitrakov
Fri May 23, 2008 9:13 pm
Forum: General Discussion
Topic: Advice on symptoms (TJ88 case)
Replies: 169
Views: 1104

Re: Prostatitis and low testosterone?

Testosterone supplements CAN predispose and trigger muscle hypertension in the prostate and increase intraprostatic pressure. Naturally, this is a general statement and might not be applicable in your case (need to have analysis on your own samples before a causal relationship can be considered) Bes...
by J Dimitrakov
Fri May 23, 2008 9:09 pm
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1015

Re: ALFUZOSIN VS. PLACEBO

A 2006 study by Dr. Nickel found alfuzosin 10mg/day beneficial for LUTS, ED, and painful ejaculation : http://www.ncbi.nlm.nih.gov/pubmed/16686719 BJU Int. 2006 Jun;97(6):1242-6. The beneficial effect of alfuzosin 10 mg once daily in 'real-life' practice on lower urinary tract symptoms (LUTS), qual...
by J Dimitrakov
Fri May 23, 2008 9:07 pm
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1015

Re: ALFUZOSIN VS. PLACEBO

latte wrote:Also, hello to JD from San Diego. Hope you are doing well.
Thanks, latte
by J Dimitrakov
Fri May 23, 2008 2:07 am
Forum: Research News & Updates
Topic: NIDDK Meeting on Defining the Urologic CPPS - June 16/17
Replies: 11
Views: 631

Re: NIDDK Meeting on Defining the Urologic CPPS - June 08

The agenda for the meeting has been posted and is available here:

http://www3.niddk.nih.gov/fund/other/Ur ... agenda.htm

For the patients attending, here is your chance to hear and be heard

Tuesday, June 17, 2008
Session V: A Patient Advocacy Panel

Best,
JD
by J Dimitrakov
Fri May 23, 2008 2:02 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1015

Re: ALFUZOSIN VS. PLACEBO

Alpha-blockers relax smooth muscle, improve voiding symptoms, affect alpha receptors in the central nervous system and have an anti-inflammatory effect in the lower urinary tract. A treatment effect in randomized clinical trials is noted with alpha-blockers, especially in patients not previously ta...
by J Dimitrakov
Tue May 20, 2008 2:38 am
Forum: General Discussion
Topic: Bodybuilding, steroids and prostatitis
Replies: 11
Views: 462

Re: Bodybuilding, steroids and prostatitis

There were several posts from way back on google groups about androstenedione, a testosterone precursor eg http://groups.google.com/group/sci.med.prostate.prostatitis/msg/07ac331c73d6edfd Great point, webslave. Actually, there is some data to back this up now - in our adrenocortical paper we measur...
by J Dimitrakov
Mon May 19, 2008 5:16 pm
Forum: General Discussion
Topic: Bodybuilding, steroids and prostatitis
Replies: 11
Views: 462

Re: Bodybuilding, steroids and prostatitis

Perhaps this would help point to the muscles as the primary reason for Prostatitis/CPPS given the extreme stress many of these men place on their muscles in the pelvic area. Actually, at least in the bodybuilder/steroid users, the underlying mechanism is NOT related to muscle floor dysfunction. The...
by J Dimitrakov
Mon May 19, 2008 2:08 pm
Forum: General Discussion
Topic: Bodybuilding, steroids and prostatitis
Replies: 11
Views: 462

Re: Bodybuilding, steroids and prostatitis

The prostate is an organ I associate with old men. Surgical-gloved fingers. Not, in any way, an organ I should be aware of. And yet I was, because the benign little organ had swollen to the point where it felt like a fist-sized balloon pressed against my testicles. This is a fairly common side-effe...
by J Dimitrakov
Mon May 19, 2008 3:23 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1015

Re: ALFUZOSIN VS. PLACEBO

I am not the right person to ask since I was not involved in the study which is why I posted the study exactly as presented in the abstract book

Best,
JD
by J Dimitrakov
Mon May 19, 2008 2:53 am
Forum: Research News & Updates
Topic: ALFUZOSIN VS. PLACEBO
Replies: 20
Views: 1015

Re: ALFUZOSIN VS. PLACEBO

The key words to remember here are: "Recently-Diagnosed And/Or Newly-Symptomatic Alpha-Blocker Naive Patients", "alfuzosin" and "12 weeks"

Best,
JD
by J Dimitrakov
Sun May 18, 2008 3:50 pm
Forum: General Discussion
Topic: Stubborn trigger points (Ramana's Case)
Replies: 168
Views: 6540

Re: Stubborn trigger points (Ramana's Case)

I can't type much because of shoulder pain :-(. But briefly I wanted to post a test which I had done 5 days before I had an anal fissure that caused the beginning of the pelvic pain(first rectal and then testicular) in April 2007. I got the test report today (long story). I followed it up partly be...