Search found 326 matches

by J Dimitrakov
Thu Aug 21, 2008 1:44 pm
Forum: General Discussion
Topic: Dr Jordan Dimitrakov
Replies: 3
Views: 385

Re: Dr Jordan Dimitrakov

superuse wrote:Just hope the Russians don't invade and interrupt the research...
I have actually been at Harvard Medical School in Boston for the past 5 years but thanks for the concern. I will be checking the forum intermittently time permitting

Best,
JD
by J Dimitrakov
Thu Aug 21, 2008 1:38 pm
Forum: Research News & Updates
Topic: Depression/Anxiety in CPPS/IC
Replies: 1
Views: 301

Re: Depression/Anxiety in CPPS/IC

Interesting study although we already know that from Myrna Weissman's studies at Columbia

best,
JD
by J Dimitrakov
Thu Aug 21, 2008 1:35 pm
Forum: Research News & Updates
Topic: Adrenocortical Hormone Abnormalities in Men with CP/CPPS
Replies: 158
Views: 6424

Re: Adrenocortical Hormone Abnormalities in Men with CP/CPPS

I'm just thinking here wondering if the HPA Axis in men like us is on the fritz then what will potentially be done about it? The HPA abnormalities in CPPS will most likely fall across a spectrum. Several key elements of the puzzle are still missing, e.g. what are the abnormalities at the level of t...
by J Dimitrakov
Thu Aug 21, 2008 1:31 pm
Forum: Research News & Updates
Topic: Masters in Urology 2008 - Take Home Message - Prostatitis
Replies: 4
Views: 306

Re: Masters in Urology 2008 - Take Home Message - Prostatitis

Very interesting reports, both this one and the one on IC! It's good to see the beginnings of a paradigm shift in what's written here. They seem to be recognizing that the absence of bacteria probably means there's no bacteria in there . They're hitting on a lot of the points we discuss here on the...
by J Dimitrakov
Fri Jun 27, 2008 2:15 am
Forum: General Discussion
Topic: Stubborn trigger points (Ramana's Case)
Replies: 168
Views: 6774

Re: Stubborn trigger points (Ramana's Case)

Update: So reverse T3/ DHEA-S/ Pregnelone are high. Doc who ordered this says this shows body is in high stress response state. Interesting. Pregnenolone was also found to be higher in our CPPS patients as compared with controls further implicating the same pathway in the pathogenesis of CPPS. If y...
by J Dimitrakov
Thu Jun 26, 2008 10:22 pm
Forum: General Discussion
Topic: Stubborn trigger points (Ramana's Case)
Replies: 168
Views: 6774

Re: Stubborn trigger points (Ramana's Case)

Update: So reverse T3/ DHEA-S/ Pregnelone are high. Doc who ordered this says this shows body is in high stress response state. Interesting. Pregnenolone was also found to be higher in our CPPS patients as compared with controls further implicating the same pathway in the pathogenesis of CPPS. Best...
by J Dimitrakov
Mon Jun 16, 2008 3:21 pm
Forum: General Discussion
Topic: Stubborn trigger points (Ramana's Case)
Replies: 168
Views: 6774

Re: Stubborn trigger points (Ramana's Case)

Increased bariatric pressure in flight has been shown to modulate neural transmission through various mechanisms.
We reported good success with SAM-e back in 2003. Keep us posted on your progress.

Best,
JD
by J Dimitrakov
Mon Jun 16, 2008 2:49 am
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 23
Views: 2324

Re: Could Viagra cure chronic pelvic pain?

No problem, Jay! I just wanted to point this out since the results in the study you reported, even though looking at the same agent, might not be directly relevant to the CPPS population and patients might experience results which are vastly different.

Best,
JD
by J Dimitrakov
Mon Jun 16, 2008 12:50 am
Forum: Research News & Updates
Topic: Could Viagra cure chronic pelvic pain?
Replies: 23
Views: 2324

Re: Could Viagra cure chronic pelvic pain?

Does the body get used to these drugs over time and do you have to up the dosage ? Hi Gary, I did some poking around on WebMD and found this story about your question. It's a bit old, but interesting. The person who conducted the study was following men who had ED from treatment of prostate cancer....
by J Dimitrakov
Fri Jun 13, 2008 3:41 am
Forum: General Discussion
Topic: Gay men with CPPS (Popburner's Case)
Replies: 88
Views: 2093

Re: Gay men with CPPS (Popburner's Case)

However, what about when the person has been given advice from your therapist? - many people here have used wands to treat their trigger points with much success, and dare I say, without them, many would not be in their reduced pain state that they find themselves in today. Is pushing a wand inside...
by J Dimitrakov
Thu Jun 12, 2008 8:58 pm
Forum: General Discussion
Topic: Gay men with CPPS (Popburner's Case)
Replies: 88
Views: 2093

Re: Gay men with CPPS (Popburner's Case)

gary, how high up is it? I'm able to get above the prostate - it is higher than that? All the best! I hate to be the voice of reason but I would like to suggest that people avoid experimenting with wands and other non-physiologic devices. This could cause severe damage beyond repair. In our pelvic ...
by J Dimitrakov
Sun Jun 08, 2008 1:36 am
Forum: General Discussion
Topic: Gay men with CPPS (Popburner's Case)
Replies: 88
Views: 2093

Re: Gay men with CPPS (Popburner's Case)

Probably nerve cross-talk, which is why pain moves around with this condition. From the full text article by Rudick et al. (abstract of study posted below): "In addition to neurogenic inflammation restricted to a single organ, inflammatory cross talk between pelvic organs that share innervation via...
by J Dimitrakov
Fri Jun 06, 2008 10:20 pm
Forum: General Discussion
Topic: Gay men with CPPS (Popburner's Case)
Replies: 88
Views: 2093

Re: External neuromodulation

Just to clarify: transrectal electrostimulation is NOT considered "external".

Best,
JD
by J Dimitrakov
Fri Jun 06, 2008 10:16 pm
Forum: General Discussion
Topic: Mepartricin
Replies: 4
Views: 325

Re: Mepartricin

Mepartricin is a a polyene macrolide antibiotic that can lower estrogen levels in the prostate. It seems to be more useful in controlling LUTS from BPH than it does the widespread pain of CPPS. You can review the published literature at this link. Dr Dimitrakov may wish to comment since he authored...
by J Dimitrakov
Fri Jun 06, 2008 9:43 pm
Forum: Research News & Updates
Topic: Hydrodistention + Bladder Training "crucially important"
Replies: 2
Views: 354

Re: Hydrodistention + Bladder Training "crucially important"

Interesting. However, from the abstract it seems that this study doesn't determine how much of the beneficial effect is due to the hydrodistension and how much is due to bladder training. Most studies I have read on hydrodistension conclude that it is not effective (i.e. offers only temporary relie...