Search found 6 matches

by Adam Boyd
Fri Feb 06, 2004 1:21 am
Forum: Research News & Updates
Topic: RTX fails in IC clinical trial
Replies: 0
Views: 1193

RTX fails in IC clinical trial

In case you haven't heard, there's been another major disappointment - ICOS Corporation quietly announced this week that RTX - long considered one of the most promising IC treatments in the pipeline - failed to show any benefit in the treatment of IC in a multi-center U.S. clinical trial. They have ...
by Adam Boyd
Fri Feb 07, 2003 1:10 am
Forum: Research News & Updates
Topic: Perisphincteric Botox Injections
Replies: 8
Views: 2413

Short followup, no placebo group, not blinded, not randomized etc, underpowered (small cohort) ... not much to build hope on yet. You're right, this was a pilot study. These types of studies routinely precede larger randomized trials. Fortunately, Berger's study was placebo-controlled, and I'd susp...
by Adam Boyd
Thu Jan 30, 2003 12:53 am
Forum: Research News & Updates
Topic: Perisphincteric Botox Injections
Replies: 8
Views: 2413

Was there more information in the version you ordered than in the brief at Medline I ordered the full text article for $26 (USD). It contained much more information than what was included in the abstract, but unfortunately, there was no information on any long-term follow-up of any of these patient...
by Adam Boyd
Tue Jan 14, 2003 2:09 am
Forum: Research News & Updates
Topic: Schaeffer's Editorial 2003
Replies: 9
Views: 2411

Adam, maybe they are trying to work backwards, i.e. first find something that works to alleviate symptoms, then deduce what must be causing the problem. It's also the shortest route to concrete help for patients. They could spend years on the basics while men are not helped. That's my take on it. I...
by Adam Boyd
Fri Jan 10, 2003 2:13 am
Forum: Research News & Updates
Topic: Perisphincteric Botox Injections
Replies: 8
Views: 2413

Perisphincteric Botox Injections

After UW hinted at Dr. Berger's success with Botox in their press release regarding the Allen Foundation grant, I ordered a copy of a paper on the use of Botox in CPPS from the October 2000 issue of European Urology from Karger Publishers. The paper is titled, Persiphinteric Injection of Botulinum T...
by Adam Boyd
Fri Jan 10, 2003 1:49 am
Forum: Research News & Updates
Topic: Schaeffer's Editorial 2003
Replies: 9
Views: 2411

This is definitely a major turning point! Now, perhaps, important causative factors may be found more quickly - without the bacterial distraction. I think an important first step is to critically evaluate the role of inflammation in CPPS. While it probably contributes to symptoms in some men, I don'...