Search found 41 matches

by gmccormack
Thu Nov 21, 2013 8:27 pm
Forum: Research News & Updates
Topic: Tanezumab significantly reduces pain in IC
Replies: 5
Views: 871

Re: Tanezumab significantly reduces pain in IC

This might be old news to some but Tanezumab is back in the pipeline and being expedited by the FDA. Apparently, the people whose arthritis got worse were ones where pain was completely eliminated and the patients thought they could go back to an active lifestyle. I am pretty sure its being expedite...
by gmccormack
Thu Nov 14, 2013 3:43 am
Forum: Research News & Updates
Topic: New NIH Study for Interstitial Cystitis
Replies: 6
Views: 894

Re: New NIH Study for Interstitial Cystitis

Dr. Shoskes, Cyclosporine seems to be a rather strange selection for treatment. I know of a very small study on it by a group in Oklahoma, they all had their symptoms return after use. Surely, a patient couldn't stay on it indefinitely although if you subscribe to the theory that if you can allow yo...
by gmccormack
Wed Aug 14, 2013 3:11 am
Forum: Research News & Updates
Topic: Interplay of inflammatory mediators
Replies: 2
Views: 551

Re: Interplay of inflammatory mediators

Great find! Frustratingly, they ask a lot of good rhetorical questions It seems likely that the COX pathway and pro-inflammatory mediators play, at least, a fundamental role elevating the pain. I think others have tried Celebrex a COX-2 inhibitor with minimal success prolongation of pain is likely t...
by gmccormack
Fri Jun 14, 2013 1:18 am
Forum: Research News & Updates
Topic: AUA 2013, first glimpse
Replies: 2
Views: 589

Re: AUA 2013, first glimpse

Curtis Nickel is still posting bacterial stuff (microbes)? Wow
How does this guy get all the grant money?
by gmccormack
Mon Jun 27, 2011 5:39 pm
Forum: Research News & Updates
Topic: Silodosin
Replies: 1
Views: 419

Re: Silodosin

This is just another alpha blocker study, right? A newer one.

I think alpha blockers have a role in CPPS in those patients who have start and stop or split stream issues but it doesn't do anything for the pain symptoms.

I wonder if they'll do another study with Silodosin and Cipro combination?
by gmccormack
Tue May 17, 2011 3:20 am
Forum: Research News & Updates
Topic: AUA 2011 - Highlights
Replies: 4
Views: 565

Re: AUA 2011 - Highlights

Thanks for posting this. This AUA is somewhat disappointing and boring, there is nothing that sticks out as a ground breaking medication or more data on etiology of what exactly is going on in most patients diagnosed with CPPS. I researched ESWT awhile back, called several hospitals, and its only re...
by gmccormack
Tue May 10, 2011 8:00 pm
Forum: Research News & Updates
Topic: Tanezumab significantly reduces pain in IC
Replies: 5
Views: 871

Re: Tanezumab significantly reduces pain in IC

I was in this trial and Pfizer took it out of their pipeline because a small subset of patients got worse. Subsequently, 2 other big pharma took it out of their pipeline when the FDA started asking questions. The only company left in this realm is Abbot labs with one in phase I. Stepping away from C...
by gmccormack
Fri Feb 18, 2011 6:17 am
Forum: Research News & Updates
Topic: The DABBEC Phenotyping System
Replies: 11
Views: 489

Re: The DABBEC Phenotyping System

Any idea how many phenotypes exist? I agree with Dimitrakov that the condition changes over time, this makes the number of phenotypes practically endless. You could have patient A with urethral burning in 2006 - phenotype A, then in 2008 have testicle soreness - phenotype B, because the patient has ...
by gmccormack
Fri Nov 12, 2010 2:01 am
Forum: Research News & Updates
Topic: Study: PTNS effective for CPPS
Replies: 11
Views: 828

Re: Study: PTNS effective for CPPS

Not many active members here thankfully have had such surgeries, however, in my time spent researching CPPS we are such a small percentage of sufferers and I myself sometimes have become delusional in that the only ones suffering from this are on this site. When all doctors have given up on you and ...
by gmccormack
Mon Oct 25, 2010 2:32 am
Forum: Research News & Updates
Topic: Tanezumab
Replies: 5
Views: 783

Re: Tanezumab

This shocking, not only from a CPPS point of view but from an osteoarthritis point of view, this drug has helped many people obtain the unthinkable and I have seen it help CPPS/IC patients. Being a cynic I wonder if it has to do with the fact that there were rumors out that it was too expensive to p...
by gmccormack
Thu Oct 21, 2010 12:37 am
Forum: Research News & Updates
Topic: Study: PTNS effective for CPPS
Replies: 11
Views: 828

Re: Study: PTNS effective for CPPS

Superuse, You bring up some hot issues, I understand your points. I was merely posting the study results from a PTNS study sort of in response to Kevin (sham treatment question) and webslave. My secondary point was that I was shocked at how many invasive surgeries people have had. When I was at the ...
by gmccormack
Wed Oct 20, 2010 3:52 am
Forum: Research News & Updates
Topic: Study: PTNS effective for CPPS
Replies: 11
Views: 828

Re: Study: PTNS effective for CPPS

If your interested in PTNS get the full PDF report on "Percutaneous Tibial Nerve Stimulation as Neuromodulative Treatment of Chronic Pelvic Pain" from the Netherlands Journal: European Eurology It does a good job of explaining what they did, size of needle, duration of treament, etc I have...
by gmccormack
Fri Oct 15, 2010 8:34 pm
Forum: Therapists, MDs, Clinics and Sites
Topic: Smith Urology Institute
Replies: 1
Views: 497

Smith Urology Institute

I got the below list of "novel" therapies from the Smith Urology Blog , a bit interesting. Interesting the mention of Cannabinoids aka marijuana as a treatment, I had a uro once tell me I should try it. I never have, and reading posts here it apparently makes chronic prostatitis / chronic ...
by gmccormack
Wed Oct 06, 2010 2:00 am
Forum: Research News & Updates
Topic: Tanezumab
Replies: 5
Views: 783

Re: Tanezumab

I was in this study, while I dont think it helped me, I spoke to others in the trial and some did in fact have a moderate to significant decrease in pain, one woman who was clearly in pain from IC/CPPS when she first started claimed she was pain free. I have my doubts but I can't argue with it. What...
by gmccormack
Mon Oct 04, 2010 7:23 pm
Forum: Research News & Updates
Topic: New Clues to Chronic Pelvic Pain
Replies: 4
Views: 537

Re: New Clues to Chronic Pelvic Pain

Makes sense, very clearly written. But how are we so sure that the mouse has pelvic pain and how do we know the pelvic pain in the mouse is the same as mine? Same thing with Buffington and his pelvic pain cats. Do they have CPPS or do they have some cat specific urinary condition? The patch idea see...