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Differential Diagnosis Issues

Patients with "classic" prostatitis symptoms and positive cultures and/or elevated WBC may turn out to have bladder pain syndrome/interstitial cystitis (BPS/IC), invasive bladder cancer, prostate cancer (with a normal PSA), varicoceles (pain disappears after repairing them), congenital seminal vesicle obstruction, entrapped nerve pain after inguinal hernia repair and primary bladder dysfunction (complete response to pharmacotherapy aimed at bladder muscle and bladder neck problems). That's why seeing a urologist is essential.

For completeness, here is a list of some of the afflictions to which the prostate is prone (in no particular order):

For frequency and urgency, which are not necessarily part of CPPS, Campbell's Urology 2002 Edition lists these as some of the causes: